s m2 Search Results


refractive index measuring device dr-m2  (ATAGO CO)
90
ATAGO CO refractive index measuring device dr-m2
Refractive Index Measuring Device Dr M2, supplied by ATAGO CO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/abbe+s+refractiometer++atago+s+%E2%80%9Cdr+m2/us11261303-160-31-34
Average 90 stars, based on 1 article reviews
refractive index measuring device dr-m2 - by Bioz Stars, 2026-09
90/100 stars
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mytrak's m2  (MYTRAK Health System Inc)
90
MYTRAK Health System Inc mytrak's m2
Mytrak's M2, supplied by MYTRAK Health System Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/mytrak+s+m2/us11367085-1055-12-11
Average 90 stars, based on 1 article reviews
mytrak's m2 - by Bioz Stars, 2026-09
90/100 stars
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novatexx 2484, 60 l.m−2.s−1 air permeability  (Freudenberg Filtration Technologies SE & Co. KG)
90
Freudenberg Filtration Technologies SE & Co. KG novatexx 2484, 60 l.m−2.s−1 air permeability
Novatexx 2484, 60 L.M−2.S−1 Air Permeability, supplied by Freudenberg Filtration Technologies SE & Co. KG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/novatexx+2484++60+l+m+2+s+1+air+permeability/10__1016_slash_j__ces__2024__120367-48-7-19
Average 90 stars, based on 1 article reviews
novatexx 2484, 60 l.m−2.s−1 air permeability - by Bioz Stars, 2026-09
90/100 stars
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glass-fiber cross-ply [0/90]s (200g/m2)  (Corning Life Sciences)
90
Corning Life Sciences glass-fiber cross-ply [0/90]s (200g/m2)
Glass Fiber Cross Ply [0/90]S (200g/M2), supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/glass+fiber+cross+ply++0+90+s++200g+m2+/10__6000_slash_1929___5995__2022__11__06-40-16-20
Average 90 stars, based on 1 article reviews
glass-fiber cross-ply [0/90]s (200g/m2) - by Bioz Stars, 2026-09
90/100 stars
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light-emitting diode (led) blue-light strip (440 to 460 nm, 25 to 35 µmol/[m 2 · s]  (TAIWAN HIPOINT)
90
TAIWAN HIPOINT light-emitting diode (led) blue-light strip (440 to 460 nm, 25 to 35 µmol/[m 2 · s]
S. fimicola SfWC-1-GFP preferentially accumulated in the nuclei of vegetative hyphae under <t>blue-light</t> illumination and darkness conditions. (A) The localization of SfWC-1-GFP expressed in the WT was restricted in nuclei under darkness or 15- and 60-min blue-light treatments. (B) The WT strain containing H2B-mCherry and SfWC-1-GFP was grown under darkness or 15- and 60-min light induction conditions. H2B-mCherry fluorescence signal was used to monitor the location of nuclei. Live cell images of mycelial samples were collected before (DD) and after blue-light treatments for 15 and 60 min (DL15 and DL60). The <t>LED</t> blue-light intensity was 20 to 35 μmol/(m2 · s). White arrows indicate nuclear localization. The fluorescence of live cells was examined by using a spinning-disk confocal imaging system. All images were acquired under similar conditions, including illumination exposure setting and contrast enhancement.
Light Emitting Diode (Led) Blue Light Strip (440 To 460 Nm, 25 To 35 µmol/[M 2 · S], supplied by TAIWAN HIPOINT, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/light+emitting+diode++led++blue+light+strip++440+to+460+nm++25+to+35+%C2%B5mol++m+2+%C2%B7+s+/pmc06544823-562-29-44
Average 90 stars, based on 1 article reviews
light-emitting diode (led) blue-light strip (440 to 460 nm, 25 to 35 µmol/[m 2 · s] - by Bioz Stars, 2026-09
90/100 stars
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proton methanol conduc- permeation tivity flux (s/cm2) (kg/m2 · h)  (Tivity Health Inc)
90
Tivity Health Inc proton methanol conduc- permeation tivity flux (s/cm2) (kg/m2 · h)
S. fimicola SfWC-1-GFP preferentially accumulated in the nuclei of vegetative hyphae under <t>blue-light</t> illumination and darkness conditions. (A) The localization of SfWC-1-GFP expressed in the WT was restricted in nuclei under darkness or 15- and 60-min blue-light treatments. (B) The WT strain containing H2B-mCherry and SfWC-1-GFP was grown under darkness or 15- and 60-min light induction conditions. H2B-mCherry fluorescence signal was used to monitor the location of nuclei. Live cell images of mycelial samples were collected before (DD) and after blue-light treatments for 15 and 60 min (DL15 and DL60). The <t>LED</t> blue-light intensity was 20 to 35 μmol/(m2 · s). White arrows indicate nuclear localization. The fluorescence of live cells was examined by using a spinning-disk confocal imaging system. All images were acquired under similar conditions, including illumination exposure setting and contrast enhancement.
Proton Methanol Conduc Permeation Tivity Flux (S/Cm2) (Kg/M2 · H), supplied by Tivity Health Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/proton+methanol+conduc++permeation+tivity+flux++s+cm2+++kg+m2+%C2%B7+h+/us07674349-258-9-6
Average 90 stars, based on 1 article reviews
proton methanol conduc- permeation tivity flux (s/cm2) (kg/m2 · h) - by Bioz Stars, 2026-09
90/100 stars
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4( s )-hydroxyevogliptin (m2  (Corning Life Sciences)
90
Corning Life Sciences 4( s )-hydroxyevogliptin (m2
( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S <t>)-hydroxyevogliptin</t> and possible metabolites after incubation of 4( S )-hydroxyevogliptin <t>(M2)</t> with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.
4( S ) Hydroxyevogliptin (M2, supplied by Corning Life Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/4++s+++hydroxyevogliptin++m2/pmc06332232-146-10-29
Average 90 stars, based on 1 article reviews
4( s )-hydroxyevogliptin (m2 - by Bioz Stars, 2026-09
90/100 stars
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property value thermal diffusivity 2 [m2/s] 6 × 10−6  (InnoMat GmbH)
90
InnoMat GmbH property value thermal diffusivity 2 [m2/s] 6 × 10−6
( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S <t>)-hydroxyevogliptin</t> and possible metabolites after incubation of 4( S )-hydroxyevogliptin <t>(M2)</t> with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.
Property Value Thermal Diffusivity 2 [M2/S] 6 × 10−6, supplied by InnoMat GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/property+value+thermal+diffusivity+2++m2+s++6+%C3%97+10+6/10__3390_slash_app122111300-178-0-46
Average 90 stars, based on 1 article reviews
property value thermal diffusivity 2 [m2/s] 6 × 10−6 - by Bioz Stars, 2026-09
90/100 stars
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isolight at 850 μmol m−2 s−1  (TECHNOLOGICA LIMITED)
90
TECHNOLOGICA LIMITED isolight at 850 μmol m−2 s−1
( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S <t>)-hydroxyevogliptin</t> and possible metabolites after incubation of 4( S )-hydroxyevogliptin <t>(M2)</t> with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.
Isolight At 850 μmol M−2 S−1, supplied by TECHNOLOGICA LIMITED, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/isolight+at+850+%CE%BCmol+m+2+s+1/pmc06322573-240-23-31
Average 90 stars, based on 1 article reviews
isolight at 850 μmol m−2 s−1 - by Bioz Stars, 2026-09
90/100 stars
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m2 version of lightlab imaging®’s oct console  (LightLab Imaging)
90
LightLab Imaging m2 version of lightlab imaging®’s oct console
( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S <t>)-hydroxyevogliptin</t> and possible metabolites after incubation of 4( S )-hydroxyevogliptin <t>(M2)</t> with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.
M2 Version Of Lightlab Imaging®’S Oct Console, supplied by LightLab Imaging, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/m2+version+of+lightlab+imaging+%E2%80%99s+oct+console/pm20656632-123-7-5
Average 90 stars, based on 1 article reviews
m2 version of lightlab imaging®’s oct console - by Bioz Stars, 2026-09
90/100 stars
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model [(mesophenyl-dibenzimidazolate)2fe2(m2-s)] 2  (BioMimetic Therapeutics)
90
BioMimetic Therapeutics model [(mesophenyl-dibenzimidazolate)2fe2(m2-s)] 2
( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S <t>)-hydroxyevogliptin</t> and possible metabolites after incubation of 4( S )-hydroxyevogliptin <t>(M2)</t> with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.
Model [(Mesophenyl Dibenzimidazolate)2fe2(m2 S)] 2, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/model+++mesophenyl+dibenzimidazolate+2fe2+m2+s+++2/10__1039_slash_c7sc00570a-131-15-15
Average 90 stars, based on 1 article reviews
model [(mesophenyl-dibenzimidazolate)2fe2(m2-s)] 2 - by Bioz Stars, 2026-09
90/100 stars
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light intensity 300 μmol⋅m −2 ⋅s −1  (Photon Systems Instruments SRO)
90
Photon Systems Instruments SRO light intensity 300 μmol⋅m −2 ⋅s −1
( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S <t>)-hydroxyevogliptin</t> and possible metabolites after incubation of 4( S )-hydroxyevogliptin <t>(M2)</t> with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.
Light Intensity 300 μmol⋅M −2 ⋅S −1, supplied by Photon Systems Instruments SRO, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/s+m2/light+intensity+300+%CE%BCmol%E2%8B%85m++2+%E2%8B%85s++1/pmc07600875-60-22-29
Average 90 stars, based on 1 article reviews
light intensity 300 μmol⋅m −2 ⋅s −1 - by Bioz Stars, 2026-09
90/100 stars
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Image Search Results


S. fimicola SfWC-1-GFP preferentially accumulated in the nuclei of vegetative hyphae under blue-light illumination and darkness conditions. (A) The localization of SfWC-1-GFP expressed in the WT was restricted in nuclei under darkness or 15- and 60-min blue-light treatments. (B) The WT strain containing H2B-mCherry and SfWC-1-GFP was grown under darkness or 15- and 60-min light induction conditions. H2B-mCherry fluorescence signal was used to monitor the location of nuclei. Live cell images of mycelial samples were collected before (DD) and after blue-light treatments for 15 and 60 min (DL15 and DL60). The LED blue-light intensity was 20 to 35 μmol/(m2 · s). White arrows indicate nuclear localization. The fluorescence of live cells was examined by using a spinning-disk confocal imaging system. All images were acquired under similar conditions, including illumination exposure setting and contrast enhancement.

Journal: Applied and Environmental Microbiology

Article Title: The Blue-Light Photoreceptor Sfwc-1 Gene Regulates the Phototropic Response and Fruiting-Body Development in the Homothallic Ascomycete Sordaria fimicola

doi: 10.1128/AEM.02206-18

Figure Lengend Snippet: S. fimicola SfWC-1-GFP preferentially accumulated in the nuclei of vegetative hyphae under blue-light illumination and darkness conditions. (A) The localization of SfWC-1-GFP expressed in the WT was restricted in nuclei under darkness or 15- and 60-min blue-light treatments. (B) The WT strain containing H2B-mCherry and SfWC-1-GFP was grown under darkness or 15- and 60-min light induction conditions. H2B-mCherry fluorescence signal was used to monitor the location of nuclei. Live cell images of mycelial samples were collected before (DD) and after blue-light treatments for 15 and 60 min (DL15 and DL60). The LED blue-light intensity was 20 to 35 μmol/(m2 · s). White arrows indicate nuclear localization. The fluorescence of live cells was examined by using a spinning-disk confocal imaging system. All images were acquired under similar conditions, including illumination exposure setting and contrast enhancement.

Article Snippet: The light sources used in the experiment were fluorescent white light of 400 to 700 nm (30 to 40 μmol/[m 2 · s]; Goodly Electric, Taiwan) and a light-emitting diode (LED) blue-light strip (440 to 460 nm, 25 to 35 µmol/[m 2 · s]; Taiwan HiPoint, Taiwan).

Techniques: Fluorescence, Imaging

( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S )-hydroxyevogliptin and possible metabolites after incubation of 4( S )-hydroxyevogliptin (M2) with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: ( A ) Extracted ion chromatograms (EIC) of evogliptin and possible metabolites after incubation of evogliptin with human hepatocytes; ( B ) EIC of evogliptin and possible metabolites after incubation of evogliptin with pooled human liver S9 fractions in the presence of NADPH and PAPS; ( C ) EIC of 4( S )-hydroxyevogliptin and possible metabolites after incubation of 4( S )-hydroxyevogliptin (M2) with pooled human liver microsomes in the presence of NADPH and UDPGA; and ( D ) EIC of 4( R )-hydroxyevogliptin and possible metabolites after incubation of 4( R )-hydroxyevogliptin (M3) with pooled human liver microsomes in the presence of NADPH and UDPGA.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques: Incubation

Retention time and exact mass of the molecular ion of evogliptin and five metabolites identified after incubation of evogliptin with human hepatocytes, liver microsomes, and S9 fractions.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Retention time and exact mass of the molecular ion of evogliptin and five metabolites identified after incubation of evogliptin with human hepatocytes, liver microsomes, and S9 fractions.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques: Incubation

Formation rates of 4( S )-hydroxyevogliptin (M2) and 4( R )-hydroxyevogliptin (M3) from 5 and 50 μM evogliptin in human cDNA-expressed CYPs ( n = 3, mean ± SD).

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Formation rates of 4( S )-hydroxyevogliptin (M2) and 4( R )-hydroxyevogliptin (M3) from 5 and 50 μM evogliptin in human cDNA-expressed CYPs ( n = 3, mean ± SD).

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques:

Enzyme kinetics for the formation of 4( S )-hydroxyevogliptin (M2, ●) and 4( R )-hydroxyevogliptin (M3, ○) from evogliptin in ( A ) human liver microsomes; ( B ) human cDNA-expressed CYP3A4; and ( C ) by human cDNA-expressed CYP3A5.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Enzyme kinetics for the formation of 4( S )-hydroxyevogliptin (M2, ●) and 4( R )-hydroxyevogliptin (M3, ○) from evogliptin in ( A ) human liver microsomes; ( B ) human cDNA-expressed CYP3A4; and ( C ) by human cDNA-expressed CYP3A5.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques:

Enzyme kinetic parameters for the metabolism of evogliptin to 4( S )-hydroxyevogliptin (M2) and 4( R )-hydroxyevogliptin (M3) in human liver microsomes and human cDNA-expressed CYP enzymes.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Enzyme kinetic parameters for the metabolism of evogliptin to 4( S )-hydroxyevogliptin (M2) and 4( R )-hydroxyevogliptin (M3) in human liver microsomes and human cDNA-expressed CYP enzymes.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques:

Correlation between the formation rates of ( A ) 4( S )-hydroxyevogliptin (M2) and ( B ) 4( R )-hydroxyevogliptin (M3) from 10 μM (●) and 50 μM (○) evogliptin and testosterone 6β-hydroxylase activity in 10 different human liver microsomes; ( C ) Correlation of the formation rates of 4( S )-hydroxyevogliptin glucuronide (M4) from 100 μM 4( S )-hydroxyevogliptin to azidothymidine glucuronidation activity in 10 different human liver microsomes.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Correlation between the formation rates of ( A ) 4( S )-hydroxyevogliptin (M2) and ( B ) 4( R )-hydroxyevogliptin (M3) from 10 μM (●) and 50 μM (○) evogliptin and testosterone 6β-hydroxylase activity in 10 different human liver microsomes; ( C ) Correlation of the formation rates of 4( S )-hydroxyevogliptin glucuronide (M4) from 100 μM 4( S )-hydroxyevogliptin to azidothymidine glucuronidation activity in 10 different human liver microsomes.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques: Activity Assay

Effect of an anti-CYP3A4 antibody on the metabolism of evogliptin (50 μM) to ( A ) 4( S )-hydroxyevogliptin (M2) and ( B ) 4( R )-hydroxyevogliptin (M3) in pooled human liver microsomes.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Effect of an anti-CYP3A4 antibody on the metabolism of evogliptin (50 μM) to ( A ) 4( S )-hydroxyevogliptin (M2) and ( B ) 4( R )-hydroxyevogliptin (M3) in pooled human liver microsomes.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques:

Enzyme kinetics for the metabolism of 4( S )-hydroxyevogliptin (M2) to 4( S )-hydroxyevogliptin glucuronide (M4) in ( A ) pooled human liver microsomes; ( B ) human cDNA-expressed UGT2B4; and ( C ) human cDNA-expressed UGT2B7.

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Enzyme kinetics for the metabolism of 4( S )-hydroxyevogliptin (M2) to 4( S )-hydroxyevogliptin glucuronide (M4) in ( A ) pooled human liver microsomes; ( B ) human cDNA-expressed UGT2B4; and ( C ) human cDNA-expressed UGT2B7.

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques:

Formation rates of 4( S )-hydroxyevogliptin glucuronide (M4) from 50 and 300 μM 4( S )-hydroxyevogliptin (M2) in human cDNA-expressed UGTs (mean ± SD, n = 3).

Journal: Molecules

Article Title: In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations

doi: 10.3390/molecules201219808

Figure Lengend Snippet: Formation rates of 4( S )-hydroxyevogliptin glucuronide (M4) from 50 and 300 μM 4( S )-hydroxyevogliptin (M2) in human cDNA-expressed UGTs (mean ± SD, n = 3).

Article Snippet: The correlation coefficients between the formation rates of 4( S )-hydroxyevogliptin (M2) or 4( R )-hydroxyevogliptin (M3) from evogliptin and specific CYP activities in human liver microsomes provided by Corning Life Sciences were evaluated by the Pearson product–moment correlation coefficient using Sigma Stat software (ver.

Techniques: